Have you ever been in a party where you don't know anyone
or don't have anything in common with anyone?
You can say how you feel with 'Like a fish out of water'.
ex1. I once went to a company orientation done completely in Japanese.
All the other participants were speaking fluently in Business Japanese.
I felt like a fish out of water because I had no idea what they were talking about.
ex2. When I first arrived in Japan, I felt like a fish out of water because all the signs were written in kanji.